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London Regenerative Medicine Network

'Bringing the regenerative medicine, stem cell and tissue engineering community together'
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SPEAKER
Prof. Anthony Hollander
ARC Professor of Rheumatology & Tissue Engineering
University Of Bristol
MEETING
December 2008
BIOGRAPHY
Professor Anthony Hollander is the Arthritis Research Campaign Professor of Rheumatology and Tissue Engineering at the University of Bristol. He graduated with a 1st in Pharmacology from the University of Bath and obtained his PhD in Pathology at The University of Bristol. After 3 years of postdoctoral work at McGill University in Canada and 7 years as a lecturer at Sheffield University, he took up his Chair at Bristol in September 2000. He has a group of 10 postdocs and PhD students, all working on stem cell and cartilage engineering projects. He has founded a spin-out company, Azellon Ltd, that is developing a stem cell therapy for torn meniscal cartilage and is leading pre-clinical in vivo trials of the menisical repair technique that will progress to the first clinical trial in 2009/2010.
TALK
Claudia's trachea: Lessons learned for future regenerative medicine strategies
DESCRIPTION
On June 12th 2008 the first tissue-engineered trachea, created using the patient's own cells and a decellularised donor trachea as scaffold, was implanted into Claudia Castillio's airway, thereby avoiding the need to remove her left lung and allowing her to lead a near normal life. Achieving this outcome required a strong scientific rationale, a determined and multidisciplinary team, flexible regulatory authorities, some risk-taking and a modicum of luck. Despite the best attempts of Easyjet to block the project the various pieces of a complex jigsaw came together at the right time and a little bit of history was made.
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