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| SPEAKER |
| Prof Kevin Shakesheff |
| Professor of Tissue Engineering and Drug Delivery |
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University of Nottingham
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MEETING
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June 2009 |
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| BIOGRAPHY |
Professor Shakesheff is Director of the Centre for Biomolecular Sciences, a 350-researcher interdisciplinary Centre at the University of Nottingham. He applies his pharmaceutical background to the problems of regenerative medicine. He has published over 130 papers with 3000 citation to his name and is an inventor on ten patents/applications. He is co-founder of RegenTec Ltd and Critical Pharmaceuticals Ltd. In 2008 he was awarded a European Research Council Advanced Investigator Grant and his injectable bone concept won the Orthopaedics category at the Medical Futures Awards
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| TALK |
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Delivering cells and proteins: Scientific and Intellectual Property Opportunities
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| DESCRIPTION |
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The success of many regenerative medicine therapies will be dependent on the method of delivery of the cell, drug or scaffold to the site of repair. The complexity of the environment within the patient and the sensitivity of cell and drug function to that environment must be considered carefully in the development of new therapies. In the area of protein therapies for regenerative medicine, there is much to learn from the approach of the pharmaceutical industry to the formulation of biopharmaceuticals. Many biopharmaceuticals utilize specialised delivery systems that prolong function, simplify administration or control location. For cell therapies the problem of delivery is even greater due to the physical fragility and the complex biological response of cells. The problems posed by the delivery of cells and proteins also open up new opportunities for regenerative medicine. The pharmaceutical industry uses delivery systems as intellectual property (IP) assets that differentiate products after the drug patent has expired. The opportunity to use delivery systems as IP is greater in regenerative medicine than, perhaps, any other field because the functionality of the cell or drug is intimately linked to the environment created by the delivery system. This presentation will explore new delivery systems that allow cells and proteins to be injected into the body and then spontaneously form into a scaffold that promotes tissue regeneration.
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