| SPEAKER |
| Dr. Rosemary Drake |
| Chief Scientific Officer |
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The Automation Partnership
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MEETING
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March 2009 |
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| BIOGRAPHY |
Rosemary Drake is CSO of The Automation Partnership (TAP), a UK company based near Cambridge which develops innovative automated systems for use by biotech, pharma and research institutions. TAP supplied the first automated cell culture systems for scaling up mammalian cell culture in roller bottles for GMP production of a therapeutic protein some twenty years ago! Since then TAP has developed six other automated cell culture systems for a diverse range of applications including drug discovery and screening, protein expression, biologics development and now for development of new cell-based therapies. Rosemary's background is in life sciences and has worked at TAP since the company was founded. She has been responsible for originating a number of TAP's cell culture systems.
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| TALK |
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Automation: Is this the route to successful scale-up and manufacture of cell-based therapies?
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| DESCRIPTION |
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The long-term commercial success of regenerative medicine will depend on developing cost-effective methods for scaling up manufacture, and delivering the therapy to the patient. This talk will discuss some of the challenges and issues associated with processing cells for cellular therapies. Automation has the potential to offer significant benefits for labour intensive tasks such as cell expansion and processing where quality can be operator dependent. The presentation will include examples of where The Automation Partnership?s innovative technologies have been successfully applied to scale up existing manual cell culture processes - both for stem cells and in the manufacture of Regenerative Medicine products. Data will also be presented that illustrate the economics of different manufacturing approaches using standard cell culture vessels.
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